Table 3

Evaluation of predictors of an abnormal creatinine value* after the first cycle of cisplatin-based chemotherapy (logistic regression analysis)

UnivariateMultivariate
OR95% CIP valueOR95% CIP value
Age (years)
 <6211
 ≥621.430.79 to 2.570.2341.700.89 to 3.260.109
Sex
 Female11
 Male1.000.54 to 1.870.9911.270.61 to 2.630.528
Performance status
 0–111
 2–30.720.09 to 5.690.7561.040.12 to 8.780.968
Chemoradiotherapy
 No11
 Yes2.341.30 to 4.230.0052.501.26 to 4.960.009
Dose of cisplatin (mg/m2)
 6011
 75 or 801.950.68 to 5.610.2162.030.60 to 6.870.255
Magnesium supplementation
 No11
 Yes1.910.93 to 3.960.0801.630.73 to 3.650.230
Baseline creatinine value
 Normal11
 Abnormal* 16.25.62 to 46.9<0.00130.58.87 to 104<0.001
Method of hydration
 Conventional hydration11
 Short hydration0.240.08 to 0.680.0070.190.06 to 0.610.006
  • *Creatinine value higher than the upper limit of the creatinine value.