Objectives
  • To be able to clinically suspect the diagnosis of soft tissue sarcomas (STS), when appropriate, and to properly refer these patients to sarcoma reference centres for biopsy and specialised multidisciplinary treatment planning

  • To be able to collaborate with a sarcoma reference centre on the medical management of STS patients, as needed, through active clinical networking

Awareness
  • Awareness that STS are rare cancers, worth being referred to centres specialised in their treatment

  • Appreciation that STS can occur everywhere in the body and are an exceedingly variegated group of malignancies pathologically, with remarkable discrepancy rates in pathological diagnosis between reference institutions and the community

  • Recognition that first surgery is often crucial for the patient's outcome and that proper treatment should be selected on a multidisciplinary basis as from the time of diagnostic suspicion

  • Awareness that, in the localised and advanced disease settings, the indication for systemic therapies and the selection of drugs significantly depends on the pathological subtype

Knowledge
  • Knowledge of the main concepts regarding the following aspects of STS:

    • Essentials of natural history of STS in general

    • Clinical importance of histopathological partitioning (with significant subgroups, such as desmoid tumours, small round cell sarcomas, uterine sarcomas, including endometrial stromal sarcomas)

    • Gross prognostic factors

    • Objectives of surgery and radiation therapy for localised disease

    • Potential and uncertainties of adjuvant and neoadjuvant systemic therapy

    • Potential of surgery of lung metastases

    • Principles of systemic treatment of advanced disease with main active drugs

Skills
  • Ability to advise surgeons facing a clinical/pathological diagnosis of STS or suspected STS

  • Ability to refer STS patients to centres of reference by collecting and conveying essential, meaningful clinical information

  • Ability to actively discuss patient cases with reference centres in regard to strategic clinical decisions and medical treatment conduct, as needed