Table 11

Non-liver-directed therapies: SIGN recommendations

Quality of evidences (SIGN)RecommendationStrength of recommendation
BCytoreductive surgery and intraperitoneal chemohyperthermia performed in centres of expertise can be attempted in patients with isolated peritoneal carcinomatosis.70 Conditional for
D*Radiation therapy is efficacious for palliative treatment of bone metastases.Strong for
D*Radiation therapy +/- chemotherapy can be used for palliation or with a cytoreductive intent in patients with resectable recurrent disease localised in the pelvis, lymph nodes and lung.Conditional for
  • *Panel opinion.

  • SIGN, Scottish Intercollegiate Guidelines Network.