Table 2

Incidence of multiple primaries over all cancer sites in the literature

Number of patients evaluatedGeographic regionFrequency of multiple primariesMean follow-up
(years)
Definition used for multiple primary
(SEER/IACR/IARC)
Reference
19 252Italy2.4%2.5IACR 5
1 015 564 menUSA15.8%NASEER 6
951 022 women14.4%IACR
17.2%SEER
14.55IACR
334 168Victoria, Australia4.3%5IACR 8
7.7%10
12.4%20
2 919 02322 European countries6.3%NAIACR 7
57 393West of Scotland5%5IACR 4
938Netherlands7%NANA 17
1873USA7.2%5SEER 11
11.4%10
13.3%15
14.8%20
17.2%>20
1953USA2.15%20NA 14
1 635 060Italy6.3%14IACR 16
82 671Switzerland8.17%6.6IACRAuthors of this publication
  • IACR, International Association of Cancer Registries; IARC, International Agency for Research on Cancer; SEER, Surveillance Epidemiology and End Results.