Table 4

Histopathological features of biopsies taken in 90 endoscopies

Histopathological featureNo. (%)
Lamina propria cellularity
 Normal15 (17)
 Increased
  Focal7 (8)
  Patchy24 (27)
  Diffuse, superficial4 (4)
  Diffuse, transmucosal – mild24 (26)
  Diffuse, transmucosal – moderate16 (18)
  Diffuse, transmucosal – severe0 (0)
Crypt architecture
 Normal58 (64)
 Irregular – mild23 (26)
 Irregular – moderate8 (9)
 Irregular – severe1 (1)
Mucosal surface
 Flat/normal74 (82)
 Irregular15 (17)
 Villous1 (1)
Apoptotic cells in crypt epithelium
 Absent/hardly any52 (58)
 Mild28 (31)
 Moderate6 (7)
 Severe4 (4)
Extension of chronic inflammatory infiltrate into submucosa
 Not present46 (58)
 Present33 (42)
Location of intraepithelial neutrophilic infiltration
 Absent19 (21)
 Present in crypt epithelium8 (9)
 Present in superficial epithelium16 (18)
 Present in crypt and superficial epithelium47 (52)
Grade of intraepithelial neutrophilic infiltration
 None19 (21)
 Minimal15 (17)
 Mild46 (51)
 Moderate10 (11)
 Severe0 (0)
Neutrophilic crypt abscesses
 Absent34 (38)
 Mild46 (51)
 Moderate8 (9)
 Severe2 (2)
Location of intraepithelial lymphocytosis
 Absent66 (73)
 Present in crypt epithelium(5)
 Present in superficial epithelium8 (9)
 Present in crypt and superficial epithelium12 (13)
Grade of intraepithelial lymphocytosis
 Absent66 (73)
 Minimal and patchy15 (17)
 Mild6 (7)
 Moderate2 (2)
 Severe1 (1)
Mucin depletion of epithelial cells
 Not present46 (51)
 Mild32 (36)
 Moderate10 (11)
 Severe2 (2)
Ulceration
 Absent71 (79)
 Present19 (21)
Granuloma
 Absent85 (94)
 Present in lamina propria4 (5)
 Present in submucosa1 (1)