Table 2

Renal function after the first cycle of cisplatin administration

n=46% or range
Cr elevation by CTCAE
 Without G2 or more elevation by ULN Cr4597.8
 G2* Cr Elevation12.2
 Without G2 or more elevation by baseline Cr4597.8
 G2* Cr elevation12.2
Serum Cr value
 Median (mg/dL, range)0.690.44–1.31
 Estimated Cr clearance (mL/min, median)8453–155
 Calculated eGFR (mL/min, median)7942–114
  • *The patient who experienced a G2 elevation in Cr (maximum value, 1.97 mg/dL) experienced G3 chemotherapy-induced diarrhoea and exhibited a prompt improvement in the Cr level to 1.11 mg/dL after the resolution of the diarrhoea.

  • Cr, creatinine; CTCAE, Common Terminology Criteria for Adverse Events; eGFR, estimated glomerular filtration rate; ULN, upper limit of normal value.