Table 1

Changes in gene expression levels in four mantle cell lymphoma (MCL) cell lines after exposure to birabresib

SymbollogFC
A
ILMN_2109416NAPSB−1.71E+00
ILMN_1768016TNFRSF17−1.67E+00
ILMN_1719905TLR10−1.58E+00
ILMN_1671337SLC2A5−1.48E+00
ILMN_2414762TLR10−1.45E+00
ILMN_1700147VPREB3−1.33E+00
ILMN_1756595SH3TC1−1.26E+00
ILMN_1675191GAPT−1.26E+00
ILMN_2216582LYL1−1.26E+00
ILMN_1723043NAPSB−1.25E+00
ILMN_1691071FCRLA−1.22E+00
ILMN_1746148LRRC33−1.19E+00
ILMN_1738675PTPN6−1.19E+00
ILMN_1697554SASH3−1.18E+00
ILMN_1791329FCRL2−1.17E+00
ILMN_3242271GAPT−1.17E+00
ILMN_1775542FAIM3−1.16E+00
ILMN_2085862SLC15A3−1.16E+00
ILMN_1712431FAM113B−1.15E+00
ILMN_1780368GPR18−1.15E+00
ILMN_2264011GRAP−1.14E+00
ILMN_3207122LOC644563−1.14E+00
ILMN_2384056GPER−1.13E+00
ILMN_1782704CD19−1.13E+00
ILMN_1795298GPER−1.12E+00
B
ILMN_1651496HIST1H2BD1.96E+00
ILMN_1732071HIST2H2BE1.55E+00
ILMN_1792689HIST1H2AC1.55E+00
ILMN_1659047HIST2H2AA31.45E+00
ILMN_1758623HIST1H2BD1.45E+00
ILMN_1681437DCXR1.42E+00
ILMN_2144426HIST2H2AA31.36E+00
ILMN_2115340HIST2H4A1.35E+00
ILMN_3242900HIST2H2AA41.31E+00
ILMN_1813314HIST1H2BK1.27E+00
ILMN_1658702HIST1H2BJ1.27E+00
ILMN_1796179HIST1H2BK1.26E+00
ILMN_1794017SERTAD11.25E+00
ILMN_1849494EFR3B1.21E+00
ILMN_1781374TUFT11.19E+00
ILMN_1659490LOC6531581.18E+00
ILMN_1777061ZSWIM61.18E+00
ILMN_3251587LOC1000085891.12E+00
ILMN_3238233HIST2H4B1.09E+00
ILMN_1694268HES61.08E+00
ILMN_1768973HIST2H2AC1.07E+00
ILMN_1798181IRF71.04E+00
ILMN_1708728H2AFJ1.01E+00
ILMN_1748831PPP1R13B1.01E+00
ILMN_3249110CSRNP29.96E-01
  • Four MCL birabresib-treated cell lines were analysed for transcriptional changes and the resulting top 25 downregulated (A) and top 25 upregulated (B) transcripts are listed ranked by log2 ratios. logFC: log2 ratio. All p values and adjusted p values are <0.05.