Table 3

RAM-containing chemotherapy-related adverse events occurring in at least 20% of patients and grade 3 or more adverse events occurring in at least 5% of patients

G-NEC (n=17)AC (n=173)
All (%)Grades 3–4 (%)All (%)Grades 3–4 (%)
Neutropaenia15 (88)10 (59)65 (43)59 (34)
Anaemia6 (35)0 (0)60 (35)10 (6)
Thrombocytopaenia4 (24)1 (6)13 (8)4 (2)
Febrile neutropaenia1 (6)1 (6)5 (3)5 (3)
Peripheral oedema8 (47)0 (0)37 (21)0 (0)
Neuropathy6 (35)0 (0)39 (23)0 (0)
Liver injury or failure8 (47)0 (0)43 (25)0 (0)
Congestive heart failure1 (6)1 (6)0 (0)0 (0)
Gastrointestinal perforation1 (6)1 (6)2 (1)2 (1)
  • AC, adenocarcinoma; G-NEC, gastric neuroendocrine carcinoma.